Business Loans in Missouri
Scale your Missouri business with versatile financing in the Show-Me State.
540,000+
Small Businesses
$376 Billion
State GDP
$2.6 Billion
SBA Loans (Annual)
2 Major Metros
Central U.S. Location
Business Lending in Missouri
Missouri's economy benefits from its strategic central location and two major metropolitan areas: Kansas City and St. Louis. Kansas City is a national hub for animal health and nutrition (home to the Kansas City Animal Health Corridor), entrepreneurship, and logistics. St. Louis anchors a diverse economy including healthcare (led by BJC HealthCare and Washington University Medical Center), financial services, and a growing bioscience sector. The city is also a major beer brewing center, home to Anheuser-Busch InBev. Missouri's agricultural sector is substantial, ranking second nationally in beef cattle operations and among the top states for soybeans, corn, and pork. The state's central location on the Mississippi and Missouri Rivers and its major highway and rail connections create significant advantages for logistics and distribution businesses. Missouri's approximately 540,000 small businesses benefit from a moderate cost of living, competitive business tax environment, and workforce availability. The Missouri Department of Economic Development (DED) offers the Missouri Works program for payroll tax credits, BUILD Missouri Tax Credits for infrastructure, and the Missouri Technology Corporation for tech startup investment. Kansas City's entrepreneurship ecosystem, anchored by the Kauffman Foundation, is one of the most supportive in the nation.
Top Industries in Missouri
Healthcare & Biosciences
Agriculture & Food Processing
Logistics & Transportation
Financial Services
Animal Health Sciences
Advanced Manufacturing
Top Cities for Business in Missouri
Kansas City
St. Louis
Springfield
Columbia
Independence
Lee's Summit
Lending Environment
Missouri has an active lending market across both metros. The Missouri Technology Corporation invests in tech startups. Regional CDFIs like Justine Petersen and AltCap serve urban entrepreneurs. The Missouri Agricultural and Small Business Development Authority (MASBDA) offers loan guarantees. Kansas City's Kauffman Foundation creates an exceptionally supportive entrepreneurship environment.
Business Loans in Missouri: FAQs
Nearby States
Popular Business Types in Missouri
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